Full Publication List
Complete publication record in image analysis and applications
Book Chapters
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Multiatlas Segmentation
Bennett Landman, Ilwoo Lyu, Yuankai Huo, Andrew Asman
Handbook of Medical Image Computing and Computer Assisted Intervention, 137–164, 2019 · ISBN: 9780128161760
Journal Articles
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Long-term effects of preterm birth on cortical folding trajectories in early childhood
Yong Hun Jang, Jongmin Kim, Bong Gun Lee, Jeong-Kyu Hoh, Gang Yi Lee, Hyun Ho Kim, Ilwoo Lyu, Hyun Ju Lee
Brain Communications, 8(3), fcag097, 2026
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SPHARM-Reg: Unsupervised Cortical Surface Registration using Spherical Harmonics
Seungeun Lee, Seunghwan Lee, Sunghwa Ryu, Ilwoo Lyu
IEEE Transactions on Medical Imaging, 44(11), 4732–4742, 2025
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DeepPhysioRecon: Tracing Peripheral Physiology in Low Frequency fMRI Dynamics
Roza Bayrak, Colin Hansen, Jorge Salas, Nafis Ahmed, Ilwoo Lyu, Mara Mather, Yuankai Huo, Catie Chang
Imaging Neuroscience, 3, IMAG.a.163, 2025
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Local Gyrification Index and Sulcal Depth as Imaging Markers of Cognitive Decline in Alzheimer's Disease
Yongsik Sim, Changmin Seo, Young-gun Lee, Byoung Seok Ye, Ilwoo Lyu, Beomseok Sohn
Frontiers in Aging Neuroscience, 17, 1635861, 2025
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Leveraging Input-Level Feature Deformation with Guided-Attention for Sulcal Labeling
Seungeun Lee, Seunghwan Lee, Ethan Willbrand, Benjamin Parker, Silvia Bunge, Kevin Weiner, Ilwoo Lyu
IEEE Transactions on Medical Imaging, 44(2), 915–926, 2025
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Superficial White Matter across the Lifespan: Volume, Thickness, Change, and Relationship with Cortical Features
Kurt Schilling, Derek Archer, Francois Rheault, Ilwoo Lyu, Yuankai Huo, Leon Cai, Silvia Bunge, Kevin Weiner, John Gore, Adam Anderson, Bennett Landman
Brain Structure and Function, 228, 1019–1031, 2023
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Comprehensive Shape Analysis of the Cortex in Huntington's Disease
Zachary Stoebner, Kilian Hett, Ilwoo Lyu, Hans Johnson, Jane Paulsen, Jeffrey Long, Ipek Oguz
Human Brain Mapping, 44(4), 1417–1431, 2023
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Hierarchical Particle Optimization for Cortical Shape Correspondence in Temporal Lobe Resection
Yue Liu, Shunxing Bao, Dario Englot, Victoria Morgan, Warren Taylor, Ying Wei, Ipek Oguz, Bennett Landman, Ilwoo Lyu
Computers in Biology and Medicine, 152, 106414, 2023
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Integrating the BIDS Neuroimaging Data Format and Workflow Optimization for Large-Scale Medical Image Analysis
Shunxing Bao, Brian Boyd, Praitayini Kanakaraj, Karthik Ramadass, Francisco Meyer, Yuqian Liu, William Duett, Yuankai Huo, Ilwoo Lyu, David Zald, Seth Smith, Baxter Rogers, Bennett Landman
Journal of Digital Imaging, 35(6), 1576–1589, 2022
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Automated Volumetric Determination of High R₂* Regions in Substantia Nigra: A Feasibility Study of Quantifying Substantia Nigra Atrophy in Progressive Supranuclear Palsy
Abel Worku Tessema, Hansol Lee, Yelim Gong, HwaPyeong Cho, Hamdia Murad Adem, Ilwoo Lyu, Jae-Hyeok Lee, HyungJoon Cho
NMR in Biomedicine, 35(11), e4795, 2022
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SPHARM-Net: Spherical Harmonics-based Convolution for Cortical Parcellation
Seungbo Ha, Ilwoo Lyu
IEEE Transactions on Medical Imaging, 41(10), 2739–2751, 2022
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Uncovering a Tripartite Landmark in Posterior Cingulate Cortex
Ethan Willbrand, Benjamin Parker, Willa Voorhies, Jacob Miller, Ilwoo Lyu, Tyler Hallock, Lyndsey Aponik-Gremillion, Seth Koslov, Alzheimer's Disease Neuroimaging Initiative, Silvia Bunge, Brett Foster, Kevin Weiner
Science Advances, 8(36), eabn9516, 2022
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Incomplete Hippocampal Inversion: A Neurodevelopmental Mechanism for Hippocampal Shape Deformation in Schizophrenia
Maxwell Roeske, Ilwoo Lyu, Maureen McHugo, Jennifer Blackford, Neil Woodward, Stephan Heckers
Biological Psychiatry, 92(4), 314–322, 2022 · Cover Image
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Generalizing Deep Learning Brain Segmentation for Skull Removal and Intra-Cranial Measurements
Yue Liu, Yuankai Huo, Blake Dewey, Ying Wei, Ilwoo Lyu, Bennett Landman
Magnetic Resonance Imaging, 88, 44–52, 2022
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Cortical Morphology in Autism: Findings from a Cortical Shape-Adaptive Approach to Local Gyrification Indexing
Alisa Zoltowski, Ilwoo Lyu, Michelle Failla, Lisa Mash, Kacie Dunham, Jacob Feldman, Tiffany Woynaroski, Mark Wallace, Laura Barquero, Tin Nguyen, Laurie Cutting, Hakmook Kang, Bennett Landman, Carissa Cascio
Cerebral Cortex, 31(11), 5188–5205, 2021
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Body Part Regression with Self-supervision
Yucheng Tang, Riqiang Gao, Shizhong Han, Yunqiang Chen, Dashan Gao, Vishwesh Nath, Camilo Bermudez, Michael R Savona, Shunxing Bao, Ilwoo Lyu, Yuankai Huo, Bennett A Landman
IEEE Transactions on Medical Imaging, 40(5), 1499–1507, 2021
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Anatomical Texture Patterns Identify Cerebellar Distinctions between Essential Tremor and Parkinson's Disease
Kilian Hett, Ilwoo Lyu, Paula Trujillo Diaz, Alexander Lopez, Megan Aumann, Kathleen Larson, Peter Hedera, Benoit Dawant, Bennett Landman, Daniel Claassen, Ipek Oguz
Human Brain Mapping, 42(8), 2322–2331, 2021
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Labeling Lateral Prefrontal Sulci using Spherical Data Augmentation and Context-aware Training
Ilwoo Lyu, Shunxing Bao, Lingyan Hao, Jewelia Yao, Jacob Miller, Willa Voorhies, Warren Taylor, Silvia Bunge, Kevin Weiner, Bennett Landman
NeuroImage, 229, 117758, 2021
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High-resolution 3D Abdominal Segmentation with Random Patch Network Fusion
Yucheng Tang, Riqiang Gao, Ho Hin Lee, Shizhong Han, Yunqiang Chen, Dashan Gao, Vishwesh Nath, Camilo Bermudez, Michael Savona, Richard Abramson, Shunxing Bao, Ilwoo Lyu, Yuankai Huo, Bennett Landman
Medical Image Analysis, 69, 101894, 2021
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Pandora: 4-D White Matter Bundle Population-based Atlases Derived from Diffusion MRI Fiber Tractography
Colin Hansen, Qi Yang, Ilwoo Lyu, Francois Rheault, Cailey Kerley, Bramsh Qamar Chandio, Shreyas Fadnavis, Owen Williams, Andrea Shafer, Susan Resnick, David Zald, Laurie Cutting, Warren Taylor, Brian Boyd, Eleftherios Garyfallidis, Adam Anderson, Maxime Descoteaux, Bennett Landman, Kurt Schilling
Neuroinformatics, 19, 365–379, 2021
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Fast Polynomial Approximation of Heat Kernel Convolution on Manifolds and Its Application to Brain Sulcal and Gyral Graph Pattern Analysis
Shih-Gu Huang, Ilwoo Lyu, Anqi Qiu, Moo Chung
IEEE Transactions on Medical Imaging, 39(6), 2201–2212, 2020
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A Bayesian Approach to Examining Default Mode Network Functional Connectivity and Cognitive Performance in Major Depressive Disorder
Rui Wang, Kimberly Albert, Warren Taylor, Brian Boyd, Justin Blaber, Ilwoo Lyu, Bennett Landman, Jennifer Vega, Sepideh Shokouhi, Hakmook Kang
Psychiatry Research: Neuroimaging, 301, 111102, 2020
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Network Localization of Clinical, Cognitive, and Neuropsychiatric Symptoms in Alzheimer's Disease
Aaron Tetreault, Tony Phan, Dana Orlando, Ilwoo Lyu, Hakmook Kang, Bennett Landman, Ryan Darby
Brain, 143(4), 1249–1260, 2020
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Deep Learning Reveals Untapped Information for Local White-matter Fiber Reconstruction in Diffusion-weighted MRI
Vishwesh Nath, Kurt Schilling, Prasanna Parvathaneni, Colin Hansen, Allison Hainline, Yuankai Huo, Justin Blaber, Ilwoo Lyu, Vaibhav Janve, Yurui Gao, Iwona Stepniewska, Adam Anderson, Bennett Landman
Magnetic Resonance Imaging, 62, 220–227, 2019
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Hierarchical Spherical Deformation for Cortical Surface Registration
Ilwoo Lyu, Hakmook Kang, Neil Woodward, Martin Styner, Bennett Landman
Medical Image Analysis, 57, 72–88, 2019
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Improving Human Cortical Sulcal Curve Labeling in Large Scale Cross-Sectional MRI using Deep Neural Networks
Prasanna Parvathaneni, Vishwesh Nath, Maureen McHugo, Yuankai Huo, Susan Resnick, Neil Woodward, Bennett Landman, Ilwoo Lyu
Journal of Neuroscience Methods, 324, 108311, 2019
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Improved Gray Matter Surface based Spatial Statistics in Neuroimaging Studies
Prasanna Parvathaneni, Ilwoo Lyu, Yuankai Huo, Baxter Rogers, Kurt Schilling, Vishwesh Nath, Justin Blaber, Allison Hainline, Adam Anderson, Neil Woodward, Bennett Landman
Magnetic Resonance Imaging, 61, 285–295, 2019
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Registration-based Image Enhancement Improves Multi-Atlas Segmentation of the Thalamic Nuclei and Hippocampal Subfields
Shunxing Bao, Camilo Bermudez, Yuankai Huo, Prasanna Parvathaneni, William Rodriguez, Susan Resnick, Pierre-Francois D'Haese, Maureen McHugo, Stephan Heckers, Benoit Dawant, Ilwoo Lyu, Bennett Landman
Magnetic Resonance Imaging, 59, 143–152, 2019
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A Cortical Shape-Adaptive Approach to Local Gyrification Index
Ilwoo Lyu, Sun Hyung Kim, Jessica Girault, John Gilmore, Martin Styner
Medical Image Analysis, 48, 244–258, 2018
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TRACE: A Topological Graph Representation for Automatic Sulcal Curve Extraction
Ilwoo Lyu, Sun Hyung Kim, Neil Woodward, Martin Styner, Bennett Landman
IEEE Transactions on Medical Imaging, 37(7), 1653–1663, 2018
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Towards Portable Large-Scale Image Processing with High-Performance Computing
Yuankai Huo, Justin Blaber, Stephen Damon, Brian Boyd, Shunxing Bao, Prasanna Parvathaneni, Camilo Bermudez Noguera, Shikha Chaganti, Vishwesh Nath, Jasmine Greer, Ilwoo Lyu, William French, Allen Newton, Baxter Rogers, Bennett Landman
Journal of Digital Imaging, 31(3), 304–314, 2018
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Development of Cortical Shape in the Human Brain from 6 to 24 Months of Age via a Novel Measure of Shape Complexity
Sun Hyung Kim, Ilwoo Lyu, Vladimir Fonov, Clement Vachet, Heather Hazlett, Rachel Smith, Joseph Piven, Stephen Dager, Robert McKinstry, John Pruett Jr, Alan Evans, Louis Collins, Kelly Botteron, Robert Schultz, Guido Gerig, Martin Styner, The IBIS Network
NeuroImage, 135, 163–176, 2016
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Robust Estimation of Group-wise Cortical Correspondence with an Application to Macaque and Human Neuroimaging Studies
Ilwoo Lyu, Sun Hyung Kim, Joon-Kyung Seong, Sang Wook Yoo, Alan Evans, Yundi Shi, Mar Sanchez, Marc Niethammer, Martin Styner
Frontiers in Neuroscience, 9, 210, 2015
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Spectral-based Automatic Labeling and Refining of Human Cortical Sulcal Curves using Expert-Provided Examples
Ilwoo Lyu, Joon-Kyung Seong, Sung Yong Shin, Kiho Im, Jee Hoon Roh, Min-Jeong Kim, Geon Ha Kim, Jong Hun Kim, Alan Evans, Duk L. Na, Jong-Min Lee
NeuroImage, 52(1), 142–157, 2010
Refereed Conferences
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Shape-Adaptive Guidance Signal for Interactive Cortical Sulcal Labeling
Jiwon Son, Ethan Willbrand, Benjamin Parker, Kevin Weiner, Ilwoo Lyu
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2026, to appear · early accept
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Spherical Diffusion Process for Score-Guided Cortical Correspondence via Spectral Attention
Seungeun Lee, Sergey Pyatkovskiy, Jaejun Yoo, Ilwoo Lyu
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2025, LNCS15975, 544–554, Daejeon, Korea, 2025
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Extensive Spherical Region Enlargement with Isotropic Deformation for Sulcal Labeling
Seunghwan Lee, Jiwon Son, Seungeun Lee, Ethan Willbrand, Benjamin Parker, Kevin Weiner, Ilwoo Lyu
IEEE International Symposium on Biomedical Imaging (ISBI) 2025, IEEE, 1–5, Houston, TX, 2025
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Prediction of Autism Spectrum Disorder using Epigenetic, Brain, and Sensory Behavioral Factors
Yong Jeon Cheong, Jihyun Bae, Seonkyoung Lee, Ro Ji Hyeong, Hirotaka Kosaka, Ilwoo Lyu, Minyoung Jung
International Winter Conference on Brain-Computer Interface (BCI) 2024, IEEE, 1–4, Gangwon, Korea, 2024
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Ultra-high-resolution Mapping of Cortical Layers 3T-Guided 7T MRI
Karthik Ramadass, Francois Rheault, Leon Cai, Lucas Remedios, Micah DArchangel, Ilwoo Lyu, Laura Barquero, Allen Newton, Laurie Cutting, Yuankai Huo, Bennett Landman
SPIE Medical Imaging 2022, SPIE12032, 120321G, San Diego, CA, 2022 · oral presentation
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From Brain to Body: Learning Low-Frequency Respiration and Cardiac Signals from fMRI Dynamics
Roza Bayrak, Colin Hansen, Jorge Salas, Nafis Ahmed, Ilwoo Lyu, Yuankai Huo, Catie Chang
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2021, LNCS12907, 553–563, Strasbourg, France, 2021
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Random Multi-Channel Image Synthesis for Multiplexed Immunofluorescence Imaging
Shunxing Bao, Yucheng Tang, Ho Hin Lee, Riqiang Gao, Sophie Chiron, Ilwoo Lyu, Lori Coburn, Keith Wilson, Joseph Roland, Bennett Landman, Yuankai Huo
MICCAI Workshop on Computational Pathology (COMPAY) 2021, PMLR156, 1–11, Strasbourg, France, 2021
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Validation of Group-wise Registration for Surface-based Functional MRI Analysis
Chang Yu, Yue Liu, Leon Cai, Cailey Kerley, Kaiwen Xu, Katherine Aboud, Warren Taylor, Hakmook Kang, Andrea Shafer, Lori Beason-Held, Susan Resnick, Bennett Landman, Ilwoo Lyu
SPIE Medical Imaging 2021, SPIE11596, 115960X, Houston, TX, 2021
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Joint Cortical Surface and Structural Connectivity Analysis of Alzheimer's Disease
Leon Cai, Cailey Kerley, Chang Yu, Katherine Aboud, Lori Beason-Held, Andrea Shafer, Susan Resnick, Lori Jordan, Adam Anderson, Kurt Schilling, Ilwoo Lyu, Bennett Landman
SPIE Medical Imaging 2021, SPIE11596, 1159630, Houston, TX, 2021 · oral presentation
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Automatic Labeling of Cortical Sulci using Convolutional Neural Networks in a Developmental Cohort
Lingyan Hao, Shunxing Bao, Yucheng Tang, Riqiang Gao, Prasanna Parvathaneni, Jacob Miller, Willa Voorhies, Jewelia Yao, Silvia Bunge, Kevin Weiner, Bennett Landman, Ilwoo Lyu
IEEE International Symposium on Biomedical Imaging (ISBI) 2020, IEEE, 412–415, Iowa City, IA, 2020
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Cortical Surface Parcellation using Spherical Convolutional Neural Networks
Prasanna Parvathaneni, Shunxing Bao, Vishwesh Nath, Neil Woodward, Daniel Claassen, Carissa Cascio, David Zald, Yuankai Huo, Bennett Landman, Ilwoo Lyu
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2019, LNCS11766, 501–509, Shenzhen, China, 2019 · early accept, travel award
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Enabling Multi-Shell b-Value Generalizability of Data-Driven Diffusion Models with Deep SHORE
Vishwesh Nath, Ilwoo Lyu, Kurt Schilling, Prasanna Parvathaneni, Colin Hansen, Yuankai Huo, Vaibhav Janve, Yurui Gao, Iwona Stepniewska, Adam Anderson, Bennett Landman
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2019, LNCS11766, 573–581, Shenzhen, China, 2019
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Fast Polynomial Approximation to Heat Diffusion in Manifolds
Shih-Gu Huang, Ilwoo Lyu, Anqi Qiu, Moo Chung
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2019, LNCS11767, 48–56, Shenzhen, China, 2019
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Harmonizing 1.5T/3T Diffusion Weighted MRI through Development of Deep Learning Stabilized Microarchitecture Estimators
Vishwesh Nath, Samuel Remedios, Prasanna Parvathaneni, Colin Hansen, Roza Bayrak, Camilo Bermudez, Justin Blaber, Karthik Ramadass, Kurt Schilling, Vaibhav Janve, Yurui Gao, Yuankai Huo, Ilwoo Lyu, Owen Williams, Susan Resnick, Lori Beason-Held, Baxter Rogers, Iwona Stepniewska, Adam Anderson, Bennett Landman
SPIE Medical Imaging 2019, SPIE10949, 109490O, San Diego, CA, 2019 · oral presentation
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Technology Enablers for Big Data, Multi-Stage Analysis in Medical Image Processing
Shunxing Bao, Prasanna Parvathaneni, Yuankai Huo, Yogesh Barve, Andrew Plassard, Yuang Yao, Hongyang Sun, Ilwoo Lyu, David Zald, Bennett Landman, Aniruddha Gokhale
IEEE International Conference on BigData 2018, 1337–1346, Seattle, WA, 2018
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Inter-Scanner Harmonization of High Angular Resolution DW-MRI using Null Space Deep Learning
Vishwesh Nath, Kurt Schilling, Prasanna Parvathaneni, Colin Hansen, Allison Hainline, Camilo Bermudez, Samuel Remedios, Justin Blaber, Ilwoo Lyu, Vaibhav Janve, Yurui Gao, Iwona Stepniewska, Baxter Rogers, Allen Newton, Taylor Davis, Jeff Luci, Adam Anderson, Bennett Landman
MICCAI Workshop on Computational Diffusion MRI (CDMRI) 2018, MATHVISUAL46, 193–201, Granada, Spain, 2018
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Harmonization of White and Gray Matter Features in Diffusion Microarchitecture for Cross Sectional Studies
Prasanna Parvathaneni, Shunxing Bao, Allison Hainline, Yuankai Huo, Kurt Schilling, Hakmook Kang, Owen Williams, Neil Woodward, Susan Resnick, David Zald, Ilwoo Lyu, Bennett Landman
International Conference on Clinical and Medical Image Analysis (ICCMIA) 2018, LNCVB31, 21–29, 2018
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SHARD: Spherical Harmonic based Robust Outlier Detection for HARDI Methods
Vishwesh Nath, Kurt Schilling, Allison Hainline, Prasanna Parvathaneni, Justin Blaber, Ilwoo Lyu, Adam Anderson, Hakmook Kang, Allen Newton, Baxter Rogers, Bennett Landman
SPIE Medical Imaging 2018, SPIE10574, 105740X, Houston, TX, 2018 · oral presentation
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A Data Colocation Grid Framework for Big Data Medical Image Processing – Backend Design
Shunxing Bao, Yuankai Huo, Prasanna Parvathaneni, Andrew Plassard, Camilo Bermudez, Yuang Yao, Ilwoo Lyu, Aniruddha Gokhale, Bennett Landman
SPIE Medical Imaging 2018, SPIE10579, 105790A, Houston, TX, 2018 · oral presentation
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Constructing Statistically Unbiased Cortical Surface Templates Using Feature-Space Covariance
Prasanna Parvathaneni, Ilwoo Lyu, Yuankai Huo, Justin Blaber, Allison Hainline, Hakmook Kang, Neil Woodward, Bennett Landman
SPIE Medical Imaging 2018, SPIE10574, 1057406, Houston, TX, 2018 · oral presentation
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Novel Local Shape-Adaptive Gyrification Index with Application to Brain Development
Ilwoo Lyu, Sun Hyung Kim, Jessica Bullins, John Gilmore, Martin Styner
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2017, LNCS10433, 31–39, Quebec City, Canada, 2017
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Cortical Surface Shape Assessment via Sulcal/Gyral Curve-based Gyrification Index
Ilwoo Lyu, Sun Hyung Kim, Martin Styner
IEEE International Symposium on Biomedical Imaging (ISBI) 2016, IEEE, 221–224, Prague, Czech Republic, 2016 · oral presentation, finalist for best student award
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Geodesic Distances to Landmarks for Dense Correspondence on Ensembles of Complex Shapes
Manasi Datar, Ilwoo Lyu, Sun Hyung Kim, Joshua Cates, Martin Styner, Ross Whitaker
Medical Image Computing and Computer Assisted Intervention (MICCAI) 2013, LNCS8150, 19–26, Nagoya, Japan, 2013 · oral presentation
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Cortical Correspondence via Sulcal Curve-Constrained Spherical Registration with Application to Macaque Studies
Ilwoo Lyu, Sun Hyung Kim, Joon-Kyung Seong, Sang Wook Yoo, Alan Evans, Yundi Shi, Mar Sanchez, Marc Niethammer, Martin Styner
SPIE Medical Imaging 2013, SPIE8669, 86692X, Orlando, FL, 2013
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Group-Wise Cortical Correspondence via Sulcal Curve-Constrained Entropy Minimization
Ilwoo Lyu, Sun Hyung Kim, Joon-Kyung Seong, Sang Wook Yoo, Alan Evans, Yundi Shi, Mar Sanchez, Marc Niethammer, Martin Styner
Information Processing in Medical Imaging (IPMI) 2013, LNCS7917, 364–375, Asilomar, CA, 2013 · oral presentation with open-ended discussion